Efficient persistent storage for lists in Python

I have a (key, value) map where for each key I have a somewhat large list of heterogeneous lists (~max about 250 items). Each list is a mix of strings and numbers that I might want to iterate over. The key is a string. If I wanted to store such a list with thousands of such (key, value) pairs persistently for efficient retrieval what are the best options? If I use sqlite then I would need to create a table for each key and then map the lists to individual records in the database. Are there better and efficient options if the goal is fast retrieval of the list of lists for a particular key?

PS: Sorry if this is a question for some other group, if so please point me in the right direction and I will delete this post.