What's the best practice of using SQLite in UWP?

The materials related to using SQLite in UWP is really few, and I am confused about these questions when using SQLite in UWP, after reading this article:

1. Should I close a connection every time after finishing db operation?
2. Is it necessary to close a connection explicitly?
3. Is it a better practice that keeping only one connection (for example keep the instance in a singleton) and querying with it?